Clinical Trials

Clinical trials and studies about imaging technology can be found on this channel.

A new study by Rashi Mehta--a researcher with the WVU School of Medicine and Rockefeller Neuroscience Institute--finds that focused ultrasound may induce an immunological healing effect in the brains of Alzheimer's patients.

New Radiology Research Shows Promising Results for Focused Ultrasound Treatment of Alzheimer's

March 2, 2021 — West Virginia University scientists used magnetic resonance imaging (MRI) scans to show what happens ...

March 02, 2021

Findings indicate that PPC and GG are highly predictive of overall upstaging by PSMA PET/CT for patients with high-risk prostate cancer

News | PET-CT

Model Helps Predict Which Patients will Benefit Most from PSMA PET Scan

February 23, 2021 — A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center helps identify which ...

February 23, 2021

Axial FLAIR MR image shows T2 prolongation in bilateral middle cerebellar peduncles (arrows). Findings were associated with restricted diffusion and areas of T1 hypointense signal without enhancement or abnormal susceptibility. Image courtesy of American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Coronavirus (COVID-19)

COVID-19 Associated with Leukoencephalopathy on Brain MRI

February 22, 2021 — According to an open-access article in ARRS' American Journal of Roentgenology (AJR), COVID-19 ...

February 22, 2021

F-18 FES PET images of patients with ER+/PR+/HER2- invasive ductal carcinoma. Left panel: Progressive disease seen at the 8-week time-point in a patient on sequential therapy. Right panel: Stable disease through all 3 time-points, remaining on study therapy for 6.7 months until disease progression on combined vorinostat aromatase inhibitor therapy. Image created by Lanell M Peterson, Research Scientist, University of Washington Medical Oncology, Seattle WA.

News | Molecular Imaging

Molecular Imaging Determines Effectiveness of Novel Metastatic Breast Cancer Treatment

February 22, 2021 — Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2 ...

February 22, 2021

Example MR images from paediatric brain tumour patients. This first column shows T1-weighted images following the injection of gadolinium contrast agent. The second column shows T2-weighted images and the final column shows apparent diffusion coefficient maps calculated from diffusion-weighted images. (a–c) are taken from a patient with a Pilocytic Astrocytoma, (d–f) are from a patient with an Ependymoma and (g–i) were acquired from a patient with a Medulloblastoma.

News | Pediatric Imaging

Child Brain Tumors can be Classified by Advanced Imaging and AI

February 17, 2021 — Diffusion weighted imaging and machine learning can successfully classify the diagnosis and ...

February 17, 2021

T1 structural images for the two sequences, MPRAGE and MPRAGE+PMC. The top row shows the MPRAGE sequence, while the bottom row shows the images that were generated with the MPRAGE+PMC sequence. Columns represent two different participants, one with minimal head motion (left, Low-Mover) and another with a large quantity of motion (right, High-Mover). Pial and white matter (WM) surface reconstruction from Freesurfer are also shown.

News | Magnetic Resonance Imaging (MRI)

Is it Time for a Change in How Structural MRI Data is Collected?

February 17, 2021 — A new paper, "Is it time to switch your T1W sequence? Assessing the impact of prospective motion ...

February 17, 2021

Immunotherapy-based precision medicine clinical trials being developed

News | Prostate Cancer

Why Black Men's Prostate Cancer May be More Responsive to Immunotherapy

February 16, 2021 — Black men die more often of prostate cancer yet, paradoxically, have greater survival benefits from ...

February 16, 2021

The research collaboration agreement covers a joint clinical retrospective study on liver fibrosis severity in Non-Alcoholic Steato-Hepatitis (NASH) patients

News | Artificial Intelligence

Median Technologies Signs a Major Research Collaboration Agreement with UC San Diego

February 10, 2021 — Median Technologies announced the company has signed a research collaboration agreement with the ...

February 10, 2021

Unhealthy lifestyles, various diseases, stress, and aging can all contribute to an imbalance between the production of ROS and the body's ability to reduce and eliminate them. The resulting excessive levels of ROS cause "oxidative stress".

News | Magnetic Resonance Imaging (MRI)

Novel Quantum Sensor Provides New Approach to Early Diagnosis Via Imaging

February 10, 2021 — Oxygen is essential for human life, but within the body, certain biological environmental conditions ...

February 10, 2021

Phase III clinical trial of men with a clinical suspicion of prostate cancer finds MRI with targeted biopsies to be more accurate at diagnosis and less intrusive than current standard

News | Magnetic Resonance Imaging (MRI)

Using MRI for Prostate Cancer Diagnosis Equals or Beats Current Standard

February 8, 2021 — The results of a Phase III randomized clinical trial have shown that when it comes to detecting ...

February 08, 2021

A study led by UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine shows that Black children are 18% less likely to get imaging tests as part of their emergency department visit compared to White children. Hispanic children are 13% less likely to have imaging done than Whites.

News | Pediatric Imaging

Study Shows Black or Hispanic Kids Receive Less Medical Imaging

February 3, 2021 — A study led by UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of ...

February 03, 2021

Bright spots indicate that cancer cells have responded to a one-day challenge with estrogen in this positron emission tomography (PET) scan of a woman with breast cancer. In a small study, researchers at Washington University School of Medicine in St. Louis found that only women whose tumors responded to estrogen challenge benefited from hormone therapy. The findings could help doctors choose the treatments most likely to help their patients. Image courtesy of Farrokh Dehdashti

News | PET Imaging

Imaging Identifies Breast Cancer Patients Unlikely to Benefit from Hormone Therapy

February 3, 2021 — Hormone therapy commonly is given as a targeted treatment for women whose cancer cells carry ...

February 03, 2021

Kaplan–Meier curves for the high-risk individuals and the ones with low or medium risk according to AI-severity. The threshold to assign individuals into a high-risk group was the 2/3 quantile of the AI-severity score computed for patients of the KB development cohort. a Kaplan–Meier curves were obtained for the 150 leftover KB patients from the development cohort. b Kaplan–Meier curves were obtained for the 135 patients of the IGR validation cohort. p-values for the log-rank test were equal to 4.77e–07 (KB

News | Coronavirus (COVID-19)

Integrating Deep Learning CT-scan Model Helps Predict Severity of COVID-19 Patients

February 1, 2021 — COVID-19 vaccine distribution has begun across the globe, while many countries are still struggling ...

February 01, 2021

News | Magnetic Resonance Imaging (MRI)

Beckman Institute MRI Expertise Aids Research on Hemodialysis Therapy Patients

February 1, 2021 — Researchers at the Beckman Institute for Advanced Science and Technology were part of a collaborative ...

February 01, 2021

Ludwig Chicago Co-director Ralph Weichselbaum and Kaiting Yang, a postdoctoral researcher in Weichselbaum's lab.

News | Radiation Therapy

Ludwig Cancer Research Study Reveals How Certain Gut Bacteria Compromise Radiotherapy

January 28, 2021 — A study led by Ludwig Chicago Co-director Ralph Weichselbaum, M.D., and Yang-Xin Fu, M.D., Ph.D., of ...

January 28, 2021

The four standard views of an individual mammogram were fed into Mirai. The image encoder mapped each view to a vector, and the image aggregator combined the four view vectors into a single vector for the mammogram. In this work, we used a single shared ResNet-18 as an image encoder, and a transformer as our image aggregator. The risk factor predictor module predicted all the risk factors used in the Tyrer-Cuzick model, including age, detailed family history, and hormonal factors, from the mammogram vector.

News | Breast Imaging

Mammogram-based Breast Cancer Risk Model Could Lead to Better Screening Guidelines

January 28, 2021 — A new machine learning algorithm based on mammograms can estimate the risk of breast cancer in women ...

January 28, 2021

Most research on sleep is conducted using electroencephalography (EEG), a method that entails measuring brain activity through electrodes placed along a patient's scalp. However, Anjali Tarun, a doctoral assistant at EPFL's Medical Image Processing Laboratory within the School of Engineering, decided to investigate brain activity during sleep using magnetic resonance imaging, or MRI.

News | Magnetic Resonance Imaging (MRI)

MRI Helps Unravel the Mysteries of Sleep

January 26, 2021 — Our state of consciousness changes significantly during stages of deep sleep, just as it does in a ...

January 26, 2021

An additional external-beam radiation dose delivered directly to the tumor can benefit the prospects of men with non-metastatic prostate cancer, without causing additional side effects. The risk of relapse within five years for these men is smaller than for men who did not receive this boost, as shown by a large-scale study initiated by UMC Utrecht in collaboration with the Netherlands Cancer Institute, UZ Leuven and Radboudumc.

News | Prostate Cancer

Radiation Boost Lowers Risk of Prostate Cancer Recurrence

January 25, 2021 — An additional external-beam radiation dose delivered directly to the tumor can benefit the prospects ...

January 25, 2021

News | Ultrasound Imaging

Exact Therapeutics Announces Innovative Probe Development Collaboration With GE Healthcare

January 20, 2021 — Exact Therapeutics, a clinical stage precision medicine company, announced a collaboration with GE ...

January 20, 2021

Clinical utility of Axumin (fluciclovine F 18) being investigated in expanded areas of cancer imaging

News | PET Imaging

Blue Earth Diagnostics Announces Dosing of Initial Patient in Phase 3 REVELATE Clinical Trial of 18F-Fluciclovine PET Imaging for Detection of Recurrent Brain Metastases

January 18, 2021 — Blue Earth Diagnostics, a Bracco company and recognized leader in the development and ...

January 18, 2021