Clinical Trials

Clinical trials and studies about imaging technology can be found on this channel.

Ramon Alfredo Siochi, Ph.D. — the director of medical physics at WVU — led a task group to help ensure the accuracy of data that dictates a cancer patient's radiation therapy.

News | Radiation Oncology

WVU Researcher Leads Effort to Reduce Data-transfer Error in Radiation Therapy

July 15, 2021 — Just as helicopter traffic reporters use their "bird's eye view" to route drivers around roadblocks ...

July 15, 2021

Interviews with the 1,000 at-risk patients also led to some interesting conclusions, Fine said. Even in the early days of 3D mammography, most women interviewed had at least heard about the technology.

News | Mammography

Study of 3D Mammography Shows Fewer Callbacks for New Mexican Women

July 15, 2021 — For any type of diagnostic test, technology that helps improve the reliability of test results is a ...

July 15, 2021

In the STOIC study, readers classified CT exams as COVID positive, COVID negative or normal. The readers had access to the CT scans using a 3D image visualization web application, allowing scrolling through the entire lung volume in the coronal, sagittal or axial transverse plane. The CT scan shown here has been classified as COVID positive due to the presence of bilateral ground glass opacities and absence of features such as mucoid impaction, bronchiolar nodules, segmental, lobar consolidation. RSNA Image

Feature | Coronavirus (COVID-19) | By Dave Fornell, Editor

CT Scans Help Predict COVID Outcomes at One Month

In a new study published in Radiology of more than 10,000 patients, researchers found that chest computed tomography (CT ...

July 01, 2021

The study investigates targeted drug delivery by focused ultrasound for pancreatic cancer

News | Focused Ultrasound Therapy

University of Oxford Announces Opening of PanDox Phase 1 Study

July 1, 2021 — The University of Oxford announced commencement of enrollment for the Phase I PanDox study of ...

July 01, 2021

According to a new study, by the Harvey L. Neiman Health Policy Institute and the American College of Radiology’s National Mammography Database Committee, the most influential radiologist characteristics impacting mammography interpretive performance were geography, breast sub-specialization, performance of diagnostic mammography, and performance of diagnostic ultrasound.

News | Breast Imaging

Study Finds Radiologist Characteristics Predict Performance in Screening Mammography

June 23, 2021 — According to a new study by the Harvey L. Neiman Health Policy Institute and the American College of ...

June 23, 2021

A phase III clinical trial has validated the effectiveness of the prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL in detecting and localizing recurrent prostate cancer.

News | Prostate Cancer

PSMA-Targeted Radiotracer Pinpoints Metastatic Prostate Cancer Across Anatomic Regions

June 21, 2021 — A phase III clinical trial has validated the effectiveness of the prostate-specific membrane antigen ...

June 21, 2021

The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson Cancer Center.

News | Women's Health

Black and White Women Have Same Mutations Linked to Breast Cancer Risk

June 15, 2021 — The prevalence of genetic mutations associated with breast cancer in Black and white women is the same ...

June 15, 2021

The new X-ray scanner can provide detailed information about the internal makeup of rocks, which could be useful for archaeologists studying fossils or miners making decisions about which ore to use in their extraction facilities. Image courtesy of Joel Greenberg, Duke University

News | X-Ray

X-ray Scanner Spots Cancers and Analyzes Drugs in Minutes

June 10, 2021 — Engineers at Duke University have demonstrated a prototype X-ray scanning machine that reveals not just ...

June 10, 2021

The U.S. Food and Drug Administration (#FDA) approved #Aduhelm (#aducanumab) for the treatment of #Alzheimer’s, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.

News | PET Imaging

FDA Grants Accelerated Approval for Alzheimer’s Drug Aduhelm

June 7, 2021 — The U.S. Food and Drug Administration (FDA) approved Aduhelm (aducanumab) for the treatment of Alzheimer ...

June 07, 2021

Feature | Coronavirus (COVID-19) | By Dave Fornell, Editor

Xenon MRI Showed Alveolar Capillary Diffusion Limitation in COVID-19 Long-haulers

May 26, 2021 — There are increasing reports of persistent symptoms after a patient recovers from COVID-19, now called ...

May 26, 2021

The experimental drug avasopasem manganese protects healthy tissue while enhancing radiation's capacity to kill cancerous tumor cells by converting superoxide to hydrogen peroxide. Image courtesy of Michael Story, Ph.D.

News | Radiation Therapy

Experimental Drug Makes Radiation Therapy More Effective, Less Damaging

May 21, 2021 — An experimental drug that has shown promise in protecting healthy tissue from collateral damage caused by ...

May 21, 2021

The drug, known as Avasopasem manganese, is made by Galera Therapeutics. It acts like a natural enzyme called superoxide dismutase and converts superoxide into hydrogen peroxide. Based on its ability to "mop up" damaging superoxide molecules, which are produced by radiation treatment, the drug is currently in clinical trials to test its ability to protect mucosal tissue from the side-effect of radiotherapy.

News | Radiation Therapy

Hydrogen Peroxide-producing Drug Boosts Cancer-Killing Effect of Radiotherapy

May 19, 2021 — A small drug molecule that appears to protect normal tissue from the damaging effects of radiation, may ...

May 19, 2021

Chest X-ray from patient severely ill from COVID-19, showing (in white patches) infected tissue spread across the lungs. Image courtesy of Nature Publishing or npj Digital Medicine

News | Coronavirus (COVID-19)

AI Tool Uses Chest X-ray to Differentiate Worst Cases of COVID-19

May 14, 2021 — Trained to see patterns by analyzing thousands of chest X-rays, a computer program predicted with up to ...

May 14, 2021

Medical researchers at Flinders University have established a new link between high body mass index (BMI) and breast cancer survival rates — with clinical data revealing worse outcomes for early breast cancer (EBC) patients and improved survival rates in advanced breast cancer (ABC).

News | Women's Health

Decoding the Effect of Body Mass Index on Breast Cancer

May 13, 2021 — Medical researchers at Flinders University have established a new link between high body mass index (BMI) ...

May 13, 2021

After radiosurgery concurrent with nivolumab in 59-year-old patient with melanoma BM (patient 1; Supplemental Tables 3 and 5), F-18 FET PET at follow-up 12 weeks after treatment initiation (bottom row) shows significant decrease of metabolic activity (TBRmean, ?28%) compared with baseline (top row), although MRI changes were consistent with progression according to iRANO criteria. Reduction of metabolic activity was associated with stable clinical course over 10 mo. CE = contrast-enhanced. Image created by

News | PET Imaging

PET Imaging Adds Valuable Information to Brain Metastasis Monitoring

May 5, 2021 — For patients with brain metastases, amino acid positron emission tomography (PET) can provide valuable ...

May 05, 2021

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with #Down_syndrome (#DS), #researchers from #CaseWesternReserveUniversity, #ClevelandClinic, University Hospitals and other institutions detected subtle differences in the structure and function of the #hippocampus—a region of the #brain tied to memory and learning.

News | Magnetic Resonance Imaging (MRI)

Ultra-high Field MRI Detects Subtle Differences of Brain’s ‘Hippocampus’ in People with Down Syndrome

April 29, 2021 — Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome ...

April 29, 2021

$Overview of the scaphoid fracture detection pipeline, which consisted of a segmentation and detection convolutional neural network (CNN). A class activation map is calculated and visualized as a heatmap for fracture localization. Image courtesy of Radiological Society of North America$